We observed that several SNPs in SCARNA16, IQGAP2, PTPRK, GLI3, ADARB2 and NDUFV2, which have been reported to be significantly associated with several other types of hearing loss, were also significantly associated with NIHL in this study (all P values ≤ 0.05; Table S3). Here, GLI3 is linked to noise induced hearing loss.