We observed that several SNPs in SCARNA16, IQGAP2, PTPRK, GLI3, ADARB2 and NDUFV2, which have been reported to be significantly associated with several other types of hearing loss, were also significantly associated with NIHL in this study (all P values ≤ 0.05; Table S3). The gene discussed is NDUFV2; the disease is noise induced hearing loss.