This finding indicates that the rAb-hAE antibody identified from this unique hAE case might be within the heterogeneous antibody spectrum found in patients suffering from different MOG antibody associated CNS autoimmune diseases, and it is, therefore, unlikely, that the differences in histopathology between MOGAD and the hAE case is explained by the properties of the pathogenic antibody. Here, MOG is linked to hereditary angioedema.