CCND1 and hepatocellular carcinoma: Administration of the antibody-modified nanoparticles synergistically inhibited Wnt-induced signal transduction and Ras/Raf/MAPK signaling pathway; hepatocellular carcinoma cells were arrested in G0/1 phase by down-regulation of cyclin D1 expression, thus attenuating cancer cell migration by inhibiting epithelial–mesenchymal transition.