POSTN and heart failure: [43] demonstrated that AMI patients with high serum levels of periostin had a poor short-term prognosis, and serum periostin level was positively correlated with Killip grade of myocardial infarction(It is divided into 4 grades in total, including grade I:no obvious heart failure; grade II:left heart failure, lung rales < 50% lung field; grade III:acute pulmonary edema; grade IV:cardiogenic shock, There are different stages and degrees of hemodynamic changes).