CD40LG and dengue disease: Overlapping clinical features between ZIKV and DENV cases make accurate diagnosis difficult, especially in an endemic arbovirus area.10 The clinical features of DF also vary according to the age of the patient.8 Furthermore, molecular testing is not routinely available in resource-limited settings where dengue is endemic because of its cost and sophisticated technique.11 Recently, commercial rapid diagnostic tests (RDTs) for DENV (DENV RDTs) including nonstructural protein 1 antigen (NS1 Ag) and anti-dengue IgM/IgG detection assays have become increasingly available for point-of-care testing.