The most biological relevant adipocytokines pertaining to WAT dysfunction associated with clinical outcomes among HF patients are adiponectin, leptin, resistin, omentin, visfatin, angiopoietin-like protein 2, zinc-α2-glycoprotein, glypican-4, lipocalin 2, secreted frizzled-related protein 5, retinol-binding protein-4, TNF-α, IL-6, and IL-18. Here, SFRP5 is linked to hydrops fetalis.