Further analysis demonstrated that the osteomimicry remained a prognosticator even after including disease stage for adjustment in CESC (SPP1), COAD (SPARC, BGLAP, SPARC + SPP1 + BGLAP), GBM (SPP1, SPARC + SPP1 + BGLAP), HNSC (BGLAP, SPARC + SPP1 + BGLAP), KIRC (SPARC + SPP1 + BGLAP), KIRP (SPARC), LIHC (SPP1, BGLAP, SPARC + SPP1 + BGLAP), LUAD (SPP1) and LUSC (SPARC, SPARC + SPP1 + BGLAP), and harbored marginally significant prognostic value in BLCA (SPARC), LUAD (SPARC + SPP1 + BGLAP), PAAD (SPP1) and STAD (SPARC, SPARC + SPP1 + BGLAP). Here, SPARC is linked to bladder transitional cell carcinoma.