Figure 1 showed the log2-transformed values of SPARC/SPP1/BGLAP of different cancer types. The expression of SPARC and SPP1 were positively correlated in all the cancer types (Roverall2 = 0.54, p < 0.001) except KIRC (R2 = −0.14, p = 0.003), KIRP (R2 = −0.07, p = 0.237), THCA (R2 = 0.01, p = 1.000) and UCEC (R2 = 0.05, p = 0.470), but the correlation between the expression of BGLAP and SPARC/SPP1 was not prominent (R2 < 0.40 for all cancer types) (Table 1). This evidence concerns the gene SPP1 and cancer.