But in multivariate Cox proportional hazards model, only the AFP (HR = 1.732, 95% CI = 1.003–2.991, P = 0.049) and the size of tumor (HR = 1.640, 95% CI = 1.015–2.647, P = 0.43) turned out to be independent predictors for better RFS (Figures 4C,D). Here, AFP is linked to neoplasm.