A total of 11 m6A regulators had a consistent expression pattern in IDH and 1p19q subgroups, in which four genes were up-regulated (FTO, FMR1, EIF3A, and ZC3H13) and seven genes were down-regulated (ALKBH5, IGF2BP2, IGF2BP3, RBM15, WTAP, YTHDF1, and YTHDF3) in IDH mutant and 1p19q codeletion gliomas. This evidence concerns the gene YTHDF1 and central nervous system cancer.