Results showed that 19 m6A regulators were significantly higher in gliomas compared with normal brain tissue (p < 0.05) (Figure 1A); whereas no significant difference was detected between gliomas and normal tissue regarding the expression of METTL16, ALKBH5, and METTL5 (p > 0.05). The gene discussed is METTL16; the disease is central nervous system cancer.