Besides, Kaplan–Meier analysis revealed that 15 m6A regulators were independent prognostic genes and the other regulators including YTHDC1, FMR1, ZC3H13, METTL14, EIF3A, METTL3, METTL16, and IGF2BP1 were not associated the prognosis of glioma patients. This evidence concerns the gene METTL16 and central nervous system cancer.