Moreover, analysis of the TRPM7-associated interactome in neuroblastoma cells (Figure 2) identified proteins which were mainly related to the actin cytoskeleton, such as Myosin IIA, Drebrin and the Myosin phosphatase Rho-interacting protein (p116RIP) (Middelbeek et al., 2016). The gene discussed is MPRIP; the disease is neuroblastoma.