IL10 and infection: In the present work, we have also observed that there is a strong suppression of IL-10 level, which might result from increased IL-6 level, as oral imipramine treatment increased IL-6 level in SbRLD mediated infection, and this in all probability will be further enhanced with liposomal imipramine treatment as observed in the increased suppression level of IL-10 in presence of liposomal-imipramine (Figure 3A, iv)