SIGLEC family genes (SIGLEC1 or CD169, SIGLEC2 or CD22, SIGLEC3 or CD33, SIGLEC4 or MAG, SIGLEC5, SIGLEC6, SIGLEC7, SIGLEC8, SIGLEC9, SIGLEC10, SIGLEC11, SIGLEC14, SIGLEC15, SIGLEC16) were also expressed in tumor cells, and we used the cBioPortal database to find mutation status of SIGLEC family genes in different cancer types. This evidence concerns the gene SIGLEC5 and cancer.