ADNP and urinary bladder neoplasm: To verify the outcome of tumorigenesis experiments in vitro, xenograft bladder tumor models were constructed in NOD/SCID nude mice using T24.The final volume, weight, and tumor growth curve of the transplanted tumor (Figures 4A–C) revealed that compared with the negative control group, T24 cells with ADNP knockdown had significantly lower capability of tumor formation.