DDIT3 and non-small cell lung carcinoma: NSCLC cells transfected with these plasmids were subjected to curcumol treatment, the results revealed that curcumol treatment increased DR5 promoter activity in A549 and H1299 cells transfected with the pDR5/‐552 plasmid but not in those transfected with the pDR5/‐552‐mutation CHOP (Figure 4H).