The sensitivity of resistant NSCLC cells to TRAIL was correlated with an increase of extrinsic apoptosis, as evidenced by the presence of Annexin V positive, cleaved‐PARP, and cleaved‐caspase3 expression (Figure 1H), and the alteration in cell morphology (Figure S2A, Supporting Information). Here, ANXA5 is linked to non-small cell lung carcinoma.