demonstrated that the hypoxia‐dependent mesenchymal transformation is directly controlled by HIF1α (but not HIF2α), by regulating ZEB1 expression in GBM, and detected hypoxia marker (GLUT1) and mesenchymal markers (ZEB1 and YKL40) in patient‐derived tissues.[27] Knockdown or pharmacological inhibition of HIF1α can effectively reverse hypoxia‐regulated MES transformation. Here, HIF1A is linked to glioblastoma.