YAP1 and cancer: Several studies have shown that YAP1 is an oncogene highly express in numerous cancer types including bladder cancer (Liu et al., 2013), breast cancer (Kim, Jung & Koo, 2014), gastric cancer (Kang et al., 2011), hepatocellular cancer (Xu et al., 2009), nonsmall-cell lung cancer (Wang et al., 2010), and CRC (Wang et al., 2013a; Xu et al., 2009) that associate with tumor progression and poor prognosis.