Furthermore, three co-regulated genes associated with FCs were identified: GLRX, RNF13, and ABCA1. Among these genes, the roles of ABCA1 in the atherosclerotic process have been widely described, but many contradictory results have been presented, suggesting that the roles of ABCA1 in atherosclerosis need to be further explored. The gene discussed is RNF13; the disease is atherosclerosis.