PLOD1 and polycystic ovary syndrome: PCOS is a common gynecological endocrinopathy characterized by over-expressed LH triggered hyperandrogenism, chronic oligo/anovulation and polycystic ovaries morphology, with clinical manifestations described as “hirsutism, acne, irregular menstruation and subfertility” (Teede, Deeks & Moran, 2010; Teede et al., 2018).