AHR and hepatocellular carcinoma: Related reports revealed that most core DMEs were positively correlated with AHR, PXR and PPARα, and their protein expression was downregulated in nearly 50% of the patients with hepatocellular carcinoma (HCC) (Chen et al., 2014a; Chen et al., 2014b; Hu et al., 2018; Zhong et al., 2016).