Both conditions have been independently associated with thyroid dysfunction.1,2,3,4 Furthermore, thyroid disorders may destabilise the control of both HIV and DM.1,5 Thyroid hormones participate in carbohydrate metabolism, insulin secretion and pancreatic function.6 Similarly, hypothyroidism is associated with the decreased secretion of insulin from the pancreas.7 The gene discussed is INS; the disease is thyroid gland disorder.