TCF7 and neoplasm: Interestingly, among tumor-infiltrating cells the population that expressed TCF-1 corresponded to the PD-1+ CD8+ Trm T cells, only noticed in the tumors from OVA + Porins-immunized mice (Figures 7F, G; Supplementary Figure 8), which is also supported by the greater TCF-1 MFI of the CD8+ Trm T cells and the PD-1+ subset (Figure 7H).