PDGFRB and Blindness: Several features characteristic of DR including vascular permeability, pericyte loss, BRB alteration, sustained hemorrhage, intra and sub-retinal fluid accumulation, retinal collapse, and blindness were reported in postnatal day 10 mice treated with an anti-platelet derived growth factor receptor beta (PDGFRβ) monoclonal antibody (APB5) (111).