In a recent prospective cohort study of pediatric CSA-AKI, the urinary and plasma concentrations of a series of cytokines were measured during the early postoperative stage and their correlation coefficients with the progression of CSA-AKI were evaluated, in which the plasma level of IL-8, a potent proinflammatory cytokine, was found to display the best discrimination for the AKI progression after pediatric cardiac surgery (Greenberg et al., 2018). Here, CXCL8 is linked to chromosome-type aberration frequency.