Interestingly, MDA-MB-231 cells produce more lipocalin 2 (LCN2) protein compared to MCF-731, encoded by LCN2 that was downregulated in MDA-MB-231 but not MCF-7, further adding to the rationale as to why the eqMDEC secretome preferentially affects this cancer cell type. The gene discussed is LCN2; the disease is cancer.