TXNIP and metabolic syndrome: Furthermore, the glucose-associated methylation site cg19693031 in the TXNIP gene region suggestively associated with WC, triglycerides, systolic blood pressure as well as MetS as a condition (βeff = –0.004, P = 2.25 × 10−3; βeff = –0.107, P = 1.09 × 10−5; βeff = –0.003, P = 3.24 × 10−3; βeff = –0.124, P = 6.98 × 10−5, respectively), but notably not with HDL (Fig. 1, Suppl.