Activation of p-ERK pathway has been reported to induce the invasion, metastasis and EMT in PCa.20–22,31 Thus, the findings presented here suggested that miR-199b-5p-DDR1-ERK signalling axis resulted in inhibition of EMT, which ultimately led to suppressed cell growth, invasion and metastasis in PCa. The gene discussed is DDR1; the disease is posterior cortical atrophy.