In line with the in situ IHC analyses19,29 (Figs. 3f and 4f), we found that these immune cells were detected both within tumor nest and tumor septa regions of T-cell-inflamed NB samples, with DCs directly interacting with NK cells, and/or CD8+ T cells (Fig. 5a and Supplementary Figs.  8–10). Here, CD8A is linked to neoplasm.