We also analyzed the correlation between NACO3, SP1 and TERT mRNA expression in liver cancer patients in the GEO database (GEO: GSE10143), the mRNA level of SP1 was a positive correlation with the NCOA3 (R2 = 0.7367, p < 0.0001) and TERT (R2 = 0.0.401, p < 0.0001) (Fig. S2D). This evidence concerns the gene TERT and liver cancer.