PPARGC1A and Alzheimer disease: Quantitative analysis of immunofluorescence microscopy images showed lower expression of PGC1α in AD individuals, while NDAN individuals displayed levels similar to those of control individuals (ctrl vs AD, p = 0.0003; ctrl vs NDAN, p = 0.9785; AD vs NDAN, 0.0002; Fig. 6A,A′).