It is shown that >65 years of age (odds ratio [OR] 4.390; 95% confidence interval [CI] 1.727–11.155; p = 0.002), CRP > 11 mg/L (OR 4.158; 95% CI 1.808–11.289; p = 0.001), PLT > 217 × 109/L (OR 2.547; 95% CI 1.068–6.073; p = 0.035), D-dimer > 1.0 mg/L (OR 3.496; 95% CI 1.483–8.237; p = 0.004), and an ASA score of III-V (OR 2.753; 95% CI 1.216–6.729; p = 0.026) were the five independent risk factors for preoperative DVT. This evidence concerns the gene CRP and deep vein thrombosis.