There are eight markers used in the Ogino panel, and the rate of CIMP-high in sporadic MSI-H CRC was 72.7% (88/121), whereas the rate of BRAF mutation was 45% (53/118); the definition of the MSI phenotype in the Ogino study [26] using 10 markers defined MSI-H as the presence of instability in ≥30% of the markers. Here, BRAF is linked to colorectal carcinoma.