DSC2 and Arrhythmogenic right ventricular dysplasia: Approximately 60% of ARVC patients carry a genetic mutation [3], with the majority of genes coding for components of the desmosomes, which are essential for the structural integrity between cardiomyocytes [4], including plakophilin-2 (PKP2), plakoglobin (JUP), desmoglein-2 (DSG2), desmocollin-2 (DSC2) and desmoplakin (DSP).