Global analysis of absolute pulmonary VRS volume by diagnosis indicated greater VRS volume in IPF compared to CTD (p = 0.003) and cHP (p = 0.003) as well as in IPAF compared to CTD (p = 0.007) and cHP (p = 0.007) (ANOVA p < 0.001) (Table 4). The gene discussed is NLRC4; the disease is idiopathic pulmonary fibrosis.