GRIN1 and schizophrenia: A highly significant association with schizophrenia was detected at the 5-prime end of GRIN1. Analysis of single variants and multiple-locus haplotypes indicated that the association is mainly generated by rs11146020 (case–control study: p = 0.0000013, OR = 0.61, 95% CI 0.50–0.74; TDT: p = 0.0019, T/NT = 79/123).