SLC7A5 and neoplasm: We further performed quantitative RT-PCR to assay for mRNA levels of SLC1A5 (or ASCT2) and SLC7A5 (part of LAT1) and confirmed reduced ASCT2 and increased LAT1 expression in 22Rv CRPC compared to CWR22Res androgen-dependent tumours (Fig. 4b).