MT-CO3 and neoplasm: We found, in both tumor masses, the m.1982G > A/(MT-RNR1) in C5 (Fig. 1a), the m.14207G > A/(MT-ND6) in C8 (Fig. 1b), the m.16078A > G/(MT-DLoop) in C9 (Fig. 1c), the m.9591G > A/(MT-COIII) in C13 (Fig. 1d), the m.3849G > A/(MT-ND1) in C19 (Fig. 1e), the m.2492 G > A/(MT-RNR2) (Fig. 1f) and the m.13633G > A/(MT-ND5) (Fig. 1g) in C27, the m.1641G > A/(MT-V) (Fig. 1h) and the m.3146G > A/(MT-RNR2) (Fig. 1i) in C30, nearly all of which were detected as heteroplasmic, likely due to an inevitable contamination with non-neoplastic cells of the tumor microenvironment.