The study by Nobles et al in 2015 did not find statistical difference after exercise intervention done during second trimester for GDM management through individually made program of 12 weeks although this study found significant statistical difference of exercise intervention program of five weeks, performed during second and third trimester on patients having GDM.13 The study of Bo S et al. reported the effects of exercises and behavioral recommendations on HBA1c and CRP. The gene discussed is CRP; the disease is gestational diabetes.