A cohort study done in March 2019 to assess levels of C reactive protein during first trimester found its elevated levels and on follow up 9% of those women developed GDM.4 Another study from Pakistan reported significantly higher levels of CRP (69%) in mothers who developed GDM as compare to mothers who did not develop GDM.5 Similarly literature shows higher levels of HbA1c in GDM as compare to non GDM patients with high sensitivity (91.3%).6 A study done in Pakistan in July 2019 found obesity and deranged glycated Hemoglobin in mothers with GDM.7 The gene discussed is CRP; the disease is gestational diabetes.