IAPP and type 2 diabetes mellitus: Rodent IAPP is not amyloidogenic25, thus to explore a potential functional association between IAPP and αSyn during β-cell amyloid formation we made use of a transgenic mouse T2D model that express human IAPP (hIAPP) in β-cells under the control of the rat insulin 2 promoter, denoted hIAPPtg mice.