Furthermore, studies have shown that several inflammatory factors, such as high sensitivity C-reactive protein (hs-CRP) and interleukin-6 (IL-6), and cardiac injury indicators, such as high-sensitivity cardiac troponin I (hs-cTnI) and N-terminal pro brain natriuretic peptide (NT-proBNP), play important roles in the progression of COVID-19 and death9. This evidence concerns the gene NPPB and COVID-19.