Histopathological examination showed (gastric body) poorly differentiated adenocarcinoma, and immunohistochemistry staining with intense positivity for ER, gross cystic disease fluid protein 15 (GCDFP-15) and cytokeratin 7 (CK7), as well as negative staining of cytokeratin 20 (CK20), caudal-related homeobox 2 (CDX2), and mammaglobin (Fig. 1B–F). This evidence concerns the gene KRT20 and adenocarcinoma.