PFN2 and small cell lung carcinoma: Interestingly, when SCID mice xenografted with PFN2-overexpressing SCLC cells were treated with exosomes originating from PFN2-knockdown SCLC cells, their tumors were smaller than those in the untreated mice (Supplementary Figure 4), implying that PFN2 may be a valuable therapeutic target for SCLC in clinical practice.