B9D2 and Meckel syndrome: Specifically, we have focused on the TZ gene B9D2, linked to both Joubert and Meckel syndromes (JBTS34 and MKS10; MIM#614175) (Bachmann-Gagescu et al., 2015; Bader et al., 2016; Cui et al., 2011; Dowdle et al., 2011; Romani et al., 2014; Slaats et al., 2016).