Another previous study [29] has shown DCE-MRI parameters of the Ktrans,kep, and Ve could be used to detect synovial inflammation in patients with early arthritis and correlated with synovial expression of the endothelial cell (EC) marker von Willebrand factor (vWF),which could facilitate the evaluation of joints inaccessible to next proper clinical examination. Here, VWF is linked to Arthritis.