ACE and acute respiratory distress syndrome: A possible association between the ACE I/D polymorphism genotype and the mortality risk of ALI/ARDS in Asians has been also demonstrated [58], whereas in Chinese patients, the ACE I/D polymorphism is a significant prognostic factor for the outcome of ARDS, patients with the II genotype have a significantly better chance of survival; however, patients with the D allele do not have an increased risk for ARDS [59].