The relationship between Tid1 and cancer progression has been extensively investigated in studies of HER2, c-Met receptor tyrosine kinase (MetR), signal transducer and activator of transcription 5 b (STAT5b), Akt, adenomatous polyposis coli, and galectin-7 [30,31,46,67,68,69]. This evidence concerns the gene ERBB2 and cancer.