Interestingly, others tumor suppressors, e.g., Bax-interacting factor-1 (BIF-1) and PTEN, induce autophagy, and some oncogenes, e.g., BCL-2 and extracellular signal-regulated kinase (ERK), inhibit the autophagy process [130,131,132,133]. The gene discussed is SH3GLB1; the disease is neoplasm.