In addition, since overexpression of miR-30a-5p targets CD73 and increases sensitivity of pancreas cancer to gemcitabine, the authors propose a model for mechanistic interaction between miR-30a-5p, CD73, and TNFR2, supposedly on pancreatic cancer cells and independent of adenosine generation in this scenario [83]. The gene discussed is NT5E; the disease is familial pancreatic carcinoma.