IL6 and liposarcoma: In liposarcoma, in 2017 Casadei et al. [177] reported that miR-24-3p and miR-92a-3p are released within EVs by liposarcoma cells and drive liposarcoma progression through the stimulation of the release of pro-inflammatory cytokine IL-6 from tumor-associated macrophages (TAMs) via a TLR7/8-dependent mechanism.