Additionally, all three micro-RNAs from the miRNA-106b-25 cluster were seen to target PTEN expression [150,151] and increased miRNA-106b expression recorded in CRC tissues which could target DLC-1 (while enhancing EMT, [152]) and FAT4 in CRC tissues or cell lines [153], (Table 7). This evidence concerns the gene PTEN and colorectal carcinoma.