IRS1 and hepatocellular carcinoma: Other target genes for miRNA-152 include PIK3CA in breast cancer (BC) [132] or PIK3R3 in CRC [133], EPAS1 in Paclitaxel-resistant BC cells [134], CD151 in GC [135], IGF-1R and IRS1 in BC [136], B7-H1 in GC [137], CDK8 in hepatocellular carcinoma (HCC) [138], p27 in bone marrow cells [139], SOS1 in Glioblastoma (GBM)[140] cells and KLF4 in colon cancer (CC) cells [141], (Table 5).