To understand whether the expression of P2RX4 was associated with PCa progression in clinical settings, we searched the Gene Expression Omnibus database and identified three clinical datasets, GDS1439 [34], GDS1746 [35], and GDS3289 [36], which characterized the transcriptomic profile in PCa samples and benign prostate tissues. This evidence concerns the gene P2RX4 and posterior cortical atrophy.